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Beyond macrophages, hepatic natural killer cells promote MASH progression by engaging Janus kinase (JAK)/signal transducer and activator of transcription (STAT) and nuclear factor kappa-light-enhancer of activated B cells (NF-B) signaling, elevating reactive oxygen species and proinflammatory cytokines [40]

We found that 3251 genes were differentially expressed in the liver of MMI + T3-5d mice compared to MMI mice (GSE184261) (Fig

(2021) further revealed that Wnt signaling activation was mediated by Paneth cells that secreted Wnt3 in the crypt, thereby accelerating intestinal stem cell proliferation

Sambiagio, N